Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Total Carbohydrate
<1 g
<1%‡
Vitamin C (as Ascorbic Acid & Sodium Ascorbate)
60 mg
67%
Vitamin B-6 (as Pyridoxine HCl)
5 mg
294%
Zinc (as Zinc Aspartate)
15 mg
136%
Top Medical Research Studies
9
We set out to investigate how zinc might help protect heart cells from damage caused by a lack of blood flow, known as myocardial ischemia-reperfusion injury (MIRI). Using H9C2 cells, which are derived from rat heart tissue, we simulated this injury by depriving these cells of oxygen and then reintroducing it while treating them with zinc.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Read More
9
We investigated the potential of vitamin B6, in the form of pyridoxal-5'-phosphate (PLP), to influence blood pressure, particularly in the context of hypertension. Our focus was on how PLP modifies angiotensin II, a peptide that plays a critical role in blood vessel constriction, transforming it into a different form known as pyruvamide-Ang II (Ang P).
By examining this transformation, we looked into its effects on calcium entry in vascular smooth muscle cells (VSMCs) as well as its binding affinity to blood pressure receptors. Through laboratory experiments using both spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY), we found that those treated with PLP experienced a significant drop in blood pressure, while the control group showed an increase after receiving angiotensin II.
This suggests that PLP could be an effective, low-cost option for managing hypertension, potentially offering a new path for treatment. Increasing PLP intake could help hypertensive individuals manage their condition more effectively and affordably.
By examining this transformation, we looked into its effects on calcium entry in vascular smooth muscle cells (VSMCs) as well as its binding affinity to blood pressure receptors. Through laboratory experiments using both spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY), we found that those treated with PLP experienced a significant drop in blood pressure, while the control group showed an increase after receiving angiotensin II.
This suggests that PLP could be an effective, low-cost option for managing hypertension, potentially offering a new path for treatment. Increasing PLP intake could help hypertensive individuals manage their condition more effectively and affordably.
Read More
9
We examined the effects of pyridoxamine, a vitamin B6 derivative, on heart damage caused by doxorubicin (DOX), a common chemotherapy drug known for its harmful impact on the heart. In our study, we used a rat model where some rats received DOX while others received a combination of DOX and pyridoxamine. We also included control groups for comparison to ensure the effectiveness of the treatment could be clearly evaluated.
Our findings showed that pyridoxamine significantly reduced the heart-related harm often associated with DOX treatment. Specifically, it helped in preserving the heart's structure and function, limiting the development of conditions like dilated cardiomyopathy. Furthermore, pyridoxamine appeared to mitigate inflammation, fibrosis, and oxidative stress, all of which can worsen heart health over time.
The treatment notably protected against iron-related cell death, restoring healthier balance in iron levels and improving overall heart condition at the genetic level. This suggests that pyridoxamine could serve as a promising new strategy to protect against heart damage in patients undergoing chemotherapy.
Our findings showed that pyridoxamine significantly reduced the heart-related harm often associated with DOX treatment. Specifically, it helped in preserving the heart's structure and function, limiting the development of conditions like dilated cardiomyopathy. Furthermore, pyridoxamine appeared to mitigate inflammation, fibrosis, and oxidative stress, all of which can worsen heart health over time.
The treatment notably protected against iron-related cell death, restoring healthier balance in iron levels and improving overall heart condition at the genetic level. This suggests that pyridoxamine could serve as a promising new strategy to protect against heart damage in patients undergoing chemotherapy.
Read More
Most Useful Reviews
9
Sore throat relief
8 people found this helpful
I tested this drug at the beginning of November when my throat hurt, which coincided with the receipt of my order. According to the instructions, with initial symptoms of the disease, it is recommended to dissolve up to 6 capsules daily; however, I only took 4. The next day, I was pleased with the result as the sore throat had disappeared. I completed the course over 6 days and recommend it. The tablets are not chewable but meant for resorption.
Read More
7.5
Quick recovery
1 people found this helpful
Excellent zinc with a superb composition. We do not take it regularly, but at the first sign of disease, I immediately take 1 tablet per day for 5-7 days, and it works swiftly. The tablet is large yet palatable, and even my 5-year-old child enjoys it. It’s advisable not to take it on an empty stomach to prevent nausea. Thank you all for the likes!
Read More
6
Reduced illness duration
Fine... Pink tablets, the size of a button, have a sweet-sour taste, but the absorption is bitter, hence I chewed them and washed them down with water. I have tried various zinc products on Ayherb, and this one proved effective when I fell ill. I took it in the second dose alongside vitamin C and echinacea, resulting in the illness lasting only 2 days. As for its impact on my hair, nails, and overall immune system, I believe it will take time to fully assess its effects, so I continue taking it.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.1
- All Researches
9
We focused our research on how zinc oxide nanoparticles (ZnONPs) might help reduce heart damage caused by cisplatin, a well-known chemotherapy drug. In this study, we used rats divided into different groups, some receiving varying doses of ZnONPs and others serving as control groups.
Our findings indicated that as the dosage of ZnONPs increased up to 50 mg/kg, there was a marked improvement in cardiovascular markers. We observed reduced levels of oxidative stress, inflammation, and cell damage in the heart tissues of those treated with ZnONPs. More specifically, measures related to heart tissue health and serum biomarkers showed that rats receiving higher doses exhibited recovery similar to that of healthy rats.
Overall, we concluded that ZnONPs serve as a protective agent against cisplatin-induced cardiotoxicity, showcasing their potential in improving heart health during cancer treatment.
Our findings indicated that as the dosage of ZnONPs increased up to 50 mg/kg, there was a marked improvement in cardiovascular markers. We observed reduced levels of oxidative stress, inflammation, and cell damage in the heart tissues of those treated with ZnONPs. More specifically, measures related to heart tissue health and serum biomarkers showed that rats receiving higher doses exhibited recovery similar to that of healthy rats.
Overall, we concluded that ZnONPs serve as a protective agent against cisplatin-induced cardiotoxicity, showcasing their potential in improving heart health during cancer treatment.
Read More
9
We set out to investigate how zinc might help protect heart cells from damage caused by a lack of blood flow, known as myocardial ischemia-reperfusion injury (MIRI). Using H9C2 cells, which are derived from rat heart tissue, we simulated this injury by depriving these cells of oxygen and then reintroducing it while treating them with zinc.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Read More
9
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
9
We examined how vitamin B6, or pyridoxine, might help protect against cardiovascular issues, specifically focusing on its effects in a model of angina in rats. The study involved administering vasopressin, which induced heart stress and ischemia, helping us assess the protective capabilities of pyridoxine.
During testing, we found that vitamin B6 effectively reduced ST-segment elevation on ECG and lowered heart rate related to the vasopressin-induced angina. Notably, it showed a dose-dependent response, with specific doses of 5 mg and 7 mg per kilogram proving particularly effective.
Interestingly, when we compared pyridoxine to amlodipine, another cardiovascular drug, we observed that pyridoxine not only performed better at reducing cardiac enzymes linked to heart damage but also suggests a novel approach to preventing coronary heart disease. However, combining pyridoxine with amlodipine raised concerns about increased adverse cardiovascular events, indicating that while pyridoxine may enhance heart protection, pairing it with certain medications could complicate treatment.
Given these findings, we believe that vitamin B6 at optimal doses may hold promise for heart disease prevention and deserves further exploration in clinical settings.
During testing, we found that vitamin B6 effectively reduced ST-segment elevation on ECG and lowered heart rate related to the vasopressin-induced angina. Notably, it showed a dose-dependent response, with specific doses of 5 mg and 7 mg per kilogram proving particularly effective.
Interestingly, when we compared pyridoxine to amlodipine, another cardiovascular drug, we observed that pyridoxine not only performed better at reducing cardiac enzymes linked to heart damage but also suggests a novel approach to preventing coronary heart disease. However, combining pyridoxine with amlodipine raised concerns about increased adverse cardiovascular events, indicating that while pyridoxine may enhance heart protection, pairing it with certain medications could complicate treatment.
Given these findings, we believe that vitamin B6 at optimal doses may hold promise for heart disease prevention and deserves further exploration in clinical settings.
Read More
9
We investigated the potential of vitamin B6, in the form of pyridoxal-5'-phosphate (PLP), to influence blood pressure, particularly in the context of hypertension. Our focus was on how PLP modifies angiotensin II, a peptide that plays a critical role in blood vessel constriction, transforming it into a different form known as pyruvamide-Ang II (Ang P).
By examining this transformation, we looked into its effects on calcium entry in vascular smooth muscle cells (VSMCs) as well as its binding affinity to blood pressure receptors. Through laboratory experiments using both spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY), we found that those treated with PLP experienced a significant drop in blood pressure, while the control group showed an increase after receiving angiotensin II.
This suggests that PLP could be an effective, low-cost option for managing hypertension, potentially offering a new path for treatment. Increasing PLP intake could help hypertensive individuals manage their condition more effectively and affordably.
By examining this transformation, we looked into its effects on calcium entry in vascular smooth muscle cells (VSMCs) as well as its binding affinity to blood pressure receptors. Through laboratory experiments using both spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY), we found that those treated with PLP experienced a significant drop in blood pressure, while the control group showed an increase after receiving angiotensin II.
This suggests that PLP could be an effective, low-cost option for managing hypertension, potentially offering a new path for treatment. Increasing PLP intake could help hypertensive individuals manage their condition more effectively and affordably.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Sore throat relief
8 people found this helpful
I tested this drug at the beginning of November when my throat hurt, which coincided with the receipt of my order. According to the instructions, with initial symptoms of the disease, it is recommended to dissolve up to 6 capsules daily; however, I only took 4. The next day, I was pleased with the result as the sore throat had disappeared. I completed the course over 6 days and recommend it. The tablets are not chewable but meant for resorption.
Read More
7.5
Quick recovery
1 people found this helpful
Excellent zinc with a superb composition. We do not take it regularly, but at the first sign of disease, I immediately take 1 tablet per day for 5-7 days, and it works swiftly. The tablet is large yet palatable, and even my 5-year-old child enjoys it. It’s advisable not to take it on an empty stomach to prevent nausea. Thank you all for the likes!
Read More
6
Reduced illness duration
Fine... Pink tablets, the size of a button, have a sweet-sour taste, but the absorption is bitter, hence I chewed them and washed them down with water. I have tried various zinc products on Ayherb, and this one proved effective when I fell ill. I took it in the second dose alongside vitamin C and echinacea, resulting in the illness lasting only 2 days. As for its impact on my hair, nails, and overall immune system, I believe it will take time to fully assess its effects, so I continue taking it.
Read More
Frequently Asked Questions
9
Sore throat relief
8 people found this helpful
I tested this drug at the beginning of November when my throat hurt, which coincided with the receipt of my order. According to the instructions, with initial symptoms of the disease, it is recommended to dissolve up to 6 capsules daily; however, I only took 4. The next day, I was pleased with the result as the sore throat had disappeared. I completed the course over 6 days and recommend it. The tablets are not chewable but meant for resorption.
7.5
Quick recovery
1 people found this helpful
Excellent zinc with a superb composition. We do not take it regularly, but at the first sign of disease, I immediately take 1 tablet per day for 5-7 days, and it works swiftly. The tablet is large yet palatable, and even my 5-year-old child enjoys it. It’s advisable not to take it on an empty stomach to prevent nausea. Thank you all for the likes!
6
Reduced illness duration
Fine... Pink tablets, the size of a button, have a sweet-sour taste, but the absorption is bitter, hence I chewed them and washed them down with water. I have tried various zinc products on Ayherb, and this one proved effective when I fell ill. I took it in the second dose alongside vitamin C and echinacea, resulting in the illness lasting only 2 days. As for its impact on my hair, nails, and overall immune system, I believe it will take time to fully assess its effects, so I continue taking it.
7
We explored the relationship between dietary zinc intake and the risk of atherosclerotic cardiovascular disease (ASCVD) in patients with diabetes mellitus (DM). Utilizing data from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018, we calculated the 10-year ASCVD risk according to established clinical guidelines. Our analysis focused on dietary zinc intake based on food recall data from the participants.
The findings suggest that sufficient dietary zinc intake could positively influence cardiovascular health in diabetes patients. This is particularly important, as diabetes is closely linked with increased oxidative stress and inflammation, two factors that contribute to the development of heart disease. While we see an association between zinc and improved heart health, it's essential to note that further research is needed. Large-scale, well-designed prospective studies should aim to clarify the specific role of zinc in this context.
Overall, our results underscore the potential benefits of zinc for cardiovascular health, particularly in individuals managing diabetes. As we delve deeper into these associations, we aim to provide clearer guidance on how dietary choices can impact health outcomes for those living with diabetes.
The findings suggest that sufficient dietary zinc intake could positively influence cardiovascular health in diabetes patients. This is particularly important, as diabetes is closely linked with increased oxidative stress and inflammation, two factors that contribute to the development of heart disease. While we see an association between zinc and improved heart health, it's essential to note that further research is needed. Large-scale, well-designed prospective studies should aim to clarify the specific role of zinc in this context.
Overall, our results underscore the potential benefits of zinc for cardiovascular health, particularly in individuals managing diabetes. As we delve deeper into these associations, we aim to provide clearer guidance on how dietary choices can impact health outcomes for those living with diabetes.
9
We set out to investigate how zinc might help protect heart cells from damage caused by a lack of blood flow, known as myocardial ischemia-reperfusion injury (MIRI). Using H9C2 cells, which are derived from rat heart tissue, we simulated this injury by depriving these cells of oxygen and then reintroducing it while treating them with zinc.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
7
Zinc's role in cardiovascular health
We explored how zinc deficiency relates to cardiovascular disease among obese adults in Serbia. By conducting a case-control study with 31 obese participants and 31 control subjects, we set out to understand how zinc affects body weight, lipid levels, and inflammation.
Our findings revealed that obese individuals had significantly lower serum zinc levels compared to those who weren't obese. We observed notable negative correlations between zinc levels and various health metrics, including body weight, body fat percentage, and triglycerides.
On the flip side, higher zinc levels correlated positively with beneficial high-density lipoproteins. Interestingly, we noted that the atherosclerotic index was significantly linked to zinc, suggesting that zinc status could play a role in assessing cardiovascular risk in obese individuals.
While this study spotlights zinc's intriguing relationship with cardiovascular risk factors, it does not specifically evaluate the benefits of zinc treatment on cardiovascular outcomes.
Our findings revealed that obese individuals had significantly lower serum zinc levels compared to those who weren't obese. We observed notable negative correlations between zinc levels and various health metrics, including body weight, body fat percentage, and triglycerides.
On the flip side, higher zinc levels correlated positively with beneficial high-density lipoproteins. Interestingly, we noted that the atherosclerotic index was significantly linked to zinc, suggesting that zinc status could play a role in assessing cardiovascular risk in obese individuals.
While this study spotlights zinc's intriguing relationship with cardiovascular risk factors, it does not specifically evaluate the benefits of zinc treatment on cardiovascular outcomes.
References
- Lyu X, Chen L, Wang W. Dietary zinc intake and 10-year atherosclerotic cardiovascular disease risk in diabetes mellitus patients: evidence from NHANES database. Thromb J. 2025;23:18. doi:10.1186/s12959-025-00693-0
- Ma YT, Laga T, Zhong CN, Zhuang BQ, Quan HL, et al. ANP Increases Zn Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts. Curr Med Sci. 2025;45:35. doi:10.1007/s11596-025-00019-1
- Al-Lbban AM. Role of zinc oxide nanoparticles supplementation on alleviate side effects of cisplatin induced cardiotoxicity in rats. Braz J Biol. 2025;84:e287764. doi:10.1590/1519-6984.287764
- Soskic S, Gluvic Z, Obradovic M, Ilincic B, Cabarkapa V, et al. A pilot study on the relationship between zinc deficiency and anthropometric and metabolic parameters in obese adults in Serbia. Scand J Clin Lab Invest. 2025;85:51. doi:10.1080/00365513.2025.2460034
- Zhang H, Zhou W, Wang X, Men H, Wang J, et al. Exacerbation by knocking-out metallothionein gene of obesity-induced cardiac remodeling is associated with the activation of CARD9 signaling. Int J Biol Sci. 2025;21:1032. doi:10.7150/ijbs.105513
- Guo J, Ma T, Wang B, Xing B, Huang L, et al. Zn protects H9C2 cardiomyocytes by alleviating MAMs-associated apoptosis and calcium signaling dysregulation. Cell Signal. 2025;127:111629. doi:10.1016/j.cellsig.2025.111629
- Azadi NA, Nakhaee S, Hassan NE, Mansouri B, Ariyaee M. Role of toxic and essential elements in sleep duration of patients with cardiovascular diseases. Sci Rep. 2025;15:2392. doi:10.1038/s41598-025-86873-4
- Rock CR, Miller SL, Allison BJ. The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13111400
- Guo X, Xiao T, Lin L, Gao Q, Lai B, et al. Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients. Front Immunol. 2024;15:1436747. doi:10.3389/fimmu.2024.1436747
- Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16172818
- Du W, Zhang S, Yang J, Fan H. Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial. Asia Pac J Clin Nutr. 2024;33:503. doi:10.6133/apjcn.202412_33(4).0005
- Zhang RY, Chen Y, Yan XQ, Zhang Y, Zhou H, et al. Association of pyridoxal 5'-phosphate (PLP) with lipid profiles: a population-based cohort study. Front Nutr. 2025;12:1545301. doi:10.3389/fnut.2025.1545301
- Al-Khawlani MA, Al-Madhagi WM, Sabati AM, ALomaisi SAMA, Al-Najar M. Protective effects of pyridoxine, amlodipine, and their combination in a vasopressin-induced angina model in rats. Naunyn Schmiedebergs Arch Pharmacol. 2025. doi:10.1007/s00210-025-03905-6
- Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413
- Lellig M, Rodríguez M, López-Baltanás R, Hermann J, Wollenhaupt J, et al. Pyridoxal-5'-phosphate: A cost-effective treatment candidate for hypertensive patients?. J Intern Med. 2024;296:435. doi:10.1111/joim.20015
- Rafinezhad M, Kheirouri S, Abbasnezhad M, Alizadeh M. What Dietary Vitamins and Minerals Might Be Associated with Paraoxonase-1 Serum Levels in Patients with Coronary Artery Disease?. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04382-3
- Ren W, Li Y, Lu C, Liu S, Shao Y, et al. Comprehensive assessment on the association of dietary vitamins with all-cause and cardiovascular mortality among individuals with prediabetes: evidence from NHANES 1999-2018. Food Funct. 2024;15:10037. doi:10.1039/d4fo02893g
- Li B, Hu M, Ma Y, Sun X, Wu D, et al. Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease. Sci Rep. 2024;14:19960. doi:10.1038/s41598-024-68413-8
- Song JW, Zhang ZS, Chen L, Wang QW, Xu JY, et al. Vitamin B-6 Prevents Heart Failure with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model. J Nutr. 2024;154:3031. doi:10.1016/j.tjnut.2024.08.006
- Pokushalov E, Ponomarenko A, Bayramova S, Garcia C, Pak I, et al. Effect of Methylfolate, Pyridoxal-5'-Phosphate, and Methylcobalamin (Soloways) Supplementation on Homocysteine and Low-Density Lipoprotein Cholesterol Levels in Patients with Methylenetetrahydrofolate Reductase, Methionine Synthase, and Methionine Synthase Reductase Polymorphisms: A Randomized Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16111550
- Wang P, Huang J, Xue F, Abuduaini M, Tao Y, et al. Associations of serum vitamin B6 status with the risks of cardiovascular, cancer, and all-cause mortality in the elderly. Front Immunol. 2024;15:1354958. doi:10.3389/fimmu.2024.1354958
- Haesen S, Verghote E, Heeren E, Wolfs E, Deluyker D, et al. Pyridoxamine Attenuates Doxorubicin-Induced Cardiomyopathy without Affecting Its Antitumor Effect on Rat Mammary Tumor Cells. Cells. 2024;13. doi:10.3390/cells13020120
- Haesen S, Jager MM, Brillouet A, de Laat I, Vastmans L, et al. Pyridoxamine Limits Cardiac Dysfunction in a Rat Model of Doxorubicin-Induced Cardiotoxicity. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13010112
